Please give me the answer to the A-level Biology Question Explain how action potentials are transmitted across synapses.
A-level Biology Help >>>>> Define the mechanism by which action potentials are transferred across synapses. |
The action potential is carried along the membrane of the presynaptic neurons in the form of a depolarisation wave and triggers the voltage gated Calcium Ion Channels. 2.) After these channels have opened, Ca2+ diffuses into the presynaptic neuron and triggers SNARE complexes. 3.) The Snare complexes are responsible for transporting Vesicles with neurotransmitters into the membrane that is presynaptic. 4.) The Vesicles become fused with the membrane, and undergo exocytosis. During this process, the NTs are released from the vesicle and move through the synapse. 5) They then spread through their Synaptic Cleft and Bind-specific receptors that are located on the Post - Synaptic Membrane. 6) This triggers Na+ channels to become open on the PSM which means that Na+ diffuses into PSN leading to depolarization, this is when the AP begins to be initiated. 7) Na+ channels are transferred back to the PreSN via reuptake channels , or degraded by enzymes.
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